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Translational Informatics, Biostatistics and Epidemiology Lab

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What do we do?

The Translational Informatics, Biostatistics and Epidemiology laboratory (TIBE Labs) led by Dr. Arthur Owora applies novel biostatistical and machine learning methodologies to different (structured and unstructured) and multiple data sources (active and passive) to generate analytics and insights regarding disease etiology, risk, and prognosis. Through collaboration with clinicians, the TIBE laboratory aims to translate such insights to inform effective clinical decision-making at point-of-care including more proactive and personalized care, for improved patient-centered outcomes in real-world healthcare settings.

Research Funding

Developing a Childhood Asthma Risk Passive Digital Marker

K01HL163462 | Owora (PI) | 12/01/2022-11/30/2026

 

To develop and determine the usability, acceptability, feasibility, and preliminary efficacy of a childhood asthma Passive Digital Marker (PDM) for early disease detection. Here, a PDM refers to a ML algorithm that can be used to retrieve and synthesize pre-existing ‘Passively’ collected mother/child dyad prognostic data (i.e., medical history) at ages 0-3 years in ‘Digital’ EHR to provide an objective and quantifiable ‘Marker’ of a child’s asthma risk and phenotype at ages 6-10 years.
 

Recent Publications

(* student mentees/advisees)

Jamshidi-Naeini J*, Roberts S, Dickinson S, Owora AH, Agley J, Zoh, RS, Chen X, Allison, DB. Factors associated with choice of behavioral weight loss program by adults with obesity. Clinical Obesity. Accepted

Holler E*, Campbell NL, Boustani M, Dexter P, Ben Miled Z, Owora A. Racial disparities in the pharmacological treatment of insomnia: A time-to-event analysis using real-world data. Sleep Health. 2023 Feb 27:S2352-7218(23)00032-3. doi: 10.1016/j.sleh.2023.02.002. Epub ahead of print. PMID: 36858835.

Beidelman ET*, Parker MA, Zoh RS, Owora AH. Service Utilization among Persons Who Inject Drugs Attending a Syringe Exchange Program in New York State. Subst Use Misuse. 2023 Feb 22:1-8. doi: 10.1080/10826084.2023.2177965. Epub ahead of print. PMID: 36814373.

Chusyd DE, Austad SN, Dickinson SL, Ejima K, Gadbury GL, Golzarri-Arroyo L, Holden RJ, Jamshidi-Naeini Y, Landsittel D, Mehta DT, Oakes JM, Owora AH, Pavela G, Rojo J, Sandel MW, Smith DL, Vorland CJ, Xun P, Zoh R, Allison DB. Randomization, design, and analysis for interdependency in aging research: no person or mouse is an island. Nature Aging. 2022 Dec 22. 2(12): 1101-1111.

Owora AH. Modeling the Natural Course of Atopic Multimorbidity: Correlates of Early-Life States and Exposures. Am J Respir Crit Care Med. 2023 Mar 1;207(5):633-634. doi: 10.1164/rccm.202211-2062LE. PMID: 36480962.

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